Series A Startups in 2026
Companies that raised a Series A this year, tracked from day one. A living directory for investors following the next wave of scaling startups.
AI-native networking hardware and software for data centers. Builds Ethernet switches (800G and 1.6T) and Cluster Software with AI reasoning for telemetry at 100-10,000x resolution of competitors. Hardware-agnostic platform works across AI chips from Nvidia and Google. Founded by Apstra CEO (sold to Juniper for ~$190M).
Precision oncology biotech harnessing epitope-level precision to create targeted cancer therapies. The Pointillist Platform identifies tumor-specific cell surface epitopes, enabling antibody-drug conjugates (ADCs) that avoid on-target/off-tumor toxicity. Lead candidate STP-100 expected in clinical studies early 2027.
Artificial Chip Intelligence platform using physics-informed deep learning models built specifically for semiconductor design. Integrates physical constraints, circuit behavior, and manufacturing difficulties into the design process, reducing chip development costs by 75% and timelines by half. Working with 30+ semiconductor design companies.
Physics-informed AI software that helps utility operators and planners manage grid reliability, optimize power distribution, and reduce bottlenecks. Creates digital twins of power grids, evaluating 10 million scenarios in 10 minutes while preserving 99.7% accuracy. Spun out of GE Vernova.
Tokenization platform that turns investment products into digital tokens tradable on blockchain networks. The Midas Staked Liquidity system enables instant redemptions for tokenized yield products. Over $1.7B in mTokens minted with $37M+ in yields distributed.
Space computing startup building an 88,000-satellite constellation to serve as orbital data centers, using near-continuous solar power in orbit to run AI compute workloads. Launched its first satellite with an Nvidia H100 GPU in November 2025. Fastest unicorn in Y Combinator history.
AI-native telepsychiatry platform that deploys AI copilots alongside psychiatrists. The all-in-one platform augments clinical decisions and automates back-office tasks, saving clinicians 30+ minutes per patient visit and 10+ hours per week. Serves patients through in-network virtual psychiatry.
Foreign exchange settlement startup specializing in high-speed fiat-to-stablecoin FX and payment infrastructure for institutional clients. Supports USD, Mexican peso, Colombian peso, and various stablecoins.
Distributed power delivery company with a patented Power Neuron platform that distributes power conversion across compact, software-coordinated modules with built-in energy storage for AI data centers, energy storage, and electric mobility.
AI-Native Radio Access Network (AI-RAN) technology company developing the Odyssey RAN software platform that transforms conventional mobile towers into edge computing hubs for AI inference, sensing, and edge intelligence.
Singapore-based blockchain infrastructure company building Strium (blockchain for tokenized securities) and JPYSC stablecoin. Aims to serve 80 million+ customers in the SBI ecosystem with a Superapp for digital asset access.
GLP-1 focused telehealth platform that partners with employers and government payers to manage GLP-1 medication usage for obesity and diabetes, building an agentic AI platform and capitated model to lower employer healthcare costs.
Construction payroll and compliance platform for specialty trade contractors. Automates wage calculations, tax adjustments, and compliance across union, prevailing wage, and multi-state environments. Reduced payroll processing from 14 hours to 27 minutes.
AI operating system for regulated industries including insurance and financial services. Originally founded as a specialty insurer, Notch pivoted to build AI agents with governance, auditability, and control for compliance-heavy workflows.
AI-powered care team platform deploying AI agents backed by expert clinicians for clinical operations and care management. Formerly known as Trovo Health.
Provides post-training data, evaluation, and reinforcement learning services for AI models using India-based workforce. Customers include Google DeepMind and Snowflake. 125 employees plus 1M+ contributor network.
AI platform automating the financial deductions process between CPG brands and retailers. AI agents log into retailer portals, classify deductions, validate against internal data, and file disputes for invalid charges. Works with 200+ retail brands.
Intelligent OS for teams and AI agents. Builds infrastructure to securely capture, model, and retrieve team context in real time. Combines user-controlled capture with unified team memory engine and proactive command center.
Building the 'brain' for humanoid robots using reinforcement learning and sim-to-real transfer from physics simulations. Founded January 2026 by ex-Nvidia researchers. Plans to deploy software to factory and warehouse customers.
Multi-silicon inference cloud platform that allows AI workloads to run simultaneously across diverse hardware types (CPUs, GPUs, high-memory systems). Claims 3x-10x inference speedup. Partners with NVIDIA, AMD, Intel, ARM, Cerebras.
Digital comics publishing and monetization platform for creators and independent publishers. Provides tools for distribution, audience building, and revenue generation in the digital comics market.
Developer-centric cybersecurity platform providing just-in-time permissions and identity security for software development teams. Secures developer identities and access across CI/CD pipelines and cloud infrastructure.
Enterprise AI platform that deploys workflow agents to extract tacit knowledge from organizational communications. Helps companies capture and operationalize institutional knowledge that typically lives in emails, chat, and meetings.
Japanese startup developing laser-based propulsion thrusters for small satellites and spacecraft. Technology enables precise orbital maneuverability without traditional chemical propellants.
AI-driven infrastructure project delivery platform that replaces static schedules and backward-looking reports with a continuously updated control system. Designed for hyperscale data centers, advanced industrial facilities, and defense environments.
Paris-based startup building AI agents for hospital administration. Agents operate on top of existing systems, learning to navigate them the way a human user would by reading screens, clicking interfaces, and entering data.
Security platform embedding real-time vulnerability checks into AI code-generation workflows. Its Agentic Coding Security Management platform helps prevent vulnerabilities as code is generated by AI coding tools.
AI-native fund administrator for private equity and venture capital, combining fund administration, portfolio management, and LP portal into a single vertically integrated platform. Grew from $1B to $15B in assets under administration in one year.
AI automation platform founded by ex-Palantir engineers that connects to existing enterprise systems, reverse-engineers how a business operates, and codifies that knowledge into auditable instructions for autonomous AI agents.
Clinical AI platform accelerating access to life-saving medications by bringing clinical intelligence directly into the patient record. Works with half of the top 20 U.S. health systems to move patients from diagnosis to therapy faster.
Digital-first funeral home platform that lets families manage logistics, documentation, and memorial services entirely online. Provides price transparency and reduces the administrative burden of traditional funeral planning. The largest independent funeral home in California, expanding to Texas and Washington.
AI-powered financial intelligence platform for the biopharma industry. Provides pharmaceutical companies with data-driven insights for commercial planning, market access, and competitive intelligence using machine learning and proprietary datasets.
AI-powered energy intelligence platform built on the most comprehensive catalog of US energy regulatory data, spanning all 50 state public utility commissions, every ISO/RTO, and FERC. Helps utilities, developers, hyperscalers, and investors make faster decisions about energy infrastructure.
Clinical-stage biopharma developing a first-in-class treatment (AP306) for hyperphosphatemia in chronic kidney disease patients. AP306 is a pan-phosphate transporter inhibitor with a Phase 2b study planned for 2026.
Sovereign advertising network that uses AI and blockchain consensus to enable privacy-preserving ad targeting, on-chain verifiable credentials, and automated revenue distribution without personal data surveillance.
FedRAMP-as-a-service platform that gives SaaS vendors the fastest path to government security authorization, reducing first-year costs by 90% with an AI-managed pre-authorized cloud environment.
Israeli-founded cybersecurity startup building an agentic AI platform that helps enterprises operationalize security by connecting business context across identity, cloud, data, and IT systems.
Builds scalable Physical AI robots (TITAN platform) for demanding industrial environments including solar installation, data centers, shipping, and manufacturing. Has 11,000+ robot orders via LOI and deep collaboration with Nvidia.
Community-centered maternal health platform (formerly Cayaba Care) providing hybrid virtual and in-person maternity care for Medicaid populations, with proven reductions in preterm births and NICU stays.
Secure AI control plane for enterprises that discovers, monitors, and governs AI agents across cloud, endpoints, code, and SaaS deployments using proprietary supervisory agents
AI-powered cybersecurity platform that runs models directly on endpoints to stop user-based threats at the source, giving enterprises real-time visibility over how users and AI copilots interact with data and services
Builds verified AI systems that use formal mathematics to prove the correctness of AI-generated code, scoring a perfect 12/12 on the Putnam Competition in December 2025
AI-enabled industrial robotics company building dexterous, adaptive robots for complex factory manufacturing tasks, spun out of Rivian Automotive in November 2025 with a focus on captured distribution through existing manufacturing partnerships.
Clinical AI agent platform that trains healthcare AI like doctors, enabling patient intake, triage, care navigation, and 24/7 patient support across 100+ languages with over 3 million encounters and zero safety incidents.
AI-native cybersecurity platform deploying autonomous AI agents that continuously scan for, detect, and respond to threats without human intervention, founded by Mandiant creator Kevin Mandia with backing from the CIA's In-Q-Tel.
AI networking infrastructure startup building novel high-radix switch systems and custom silicon to replace traditional tiered network architectures in AI data centers, enabling faster and more efficient AI training and inference.
Robotics intelligence company building FutureVision, a platform that uses video-predictive control and Direct Video Action (DVA) models to enable robots to adapt and operate autonomously in real-world manufacturing and logistics environments.
AI-powered growth engine for small and mid-sized businesses that replaces marketing agencies with specialized AI agents for SEO, paid ads, and website management. Went from zero to $10M revenue in 10 months.
Stablecoin-powered global payments and neobank platform offering USD-denominated accounts and cross-border transactions across 190+ countries, serving 1M+ users with $5B in annualized transaction volume.
B2B eCommerce platform for HVAC, plumbing, electrical, and industrial supply procurement. Offers a digital marketplace with 1M+ SKUs, competitive pricing, and streamlined purchasing for professional trade buyers and contractors.
AI-powered procurement platform that deploys autonomous agents to handle enterprise purchasing workflows. Automates vendor sourcing, negotiation, and purchase order management. Graduate of Y Combinator Summer 2023 batch.
Enterprise data quality platform that uses machine learning to automatically detect, alert, and fix data quality issues. Helps companies ensure their data pipelines produce reliable data for AI models, analytics, and business-critical applications.
Space habitat company developing the world's first commercial space station, Haven-1, designed for both crewed missions and in-space manufacturing. Founded by Stellar co-founder Jed McCaleb, the company is building a 100-meter-long rotating space station to enable long-term human habitation in orbit.
Clinical-stage biotech developing PRO-203, a potential best-in-class CD20xCD3 T-cell engager for severe autoimmune diseases including systemic sclerosis and lupus.
Smack Technologies is a frontier AI lab for national security, co-founded by MARSOC veterans. The company builds domain-specific AI models powered by deep reinforcement learning to deliver 'Decision Dominance' to the U.S. Department of Defense, allies, and partners. Its Omega and Alpha product suites enable campaign-informed planning in seconds across all time horizons.
IoT-based smart building platform providing wireless, cloud-based access control, attendance tracking, and visitor management. BLE mesh architecture replaces traditional wired systems with smartphone-based contactless entry. Product suite includes Bluetooth/NFC readers, QR scanners, biometric systems, and AI-powered video surveillance. Serves 500+ enterprise clients across India, US, and Middle East with 500,000+ users across 24M sq ft of real estate. Holds 7 patents.
AI-native defense company developing AI-powered orchestration for autonomous systems. Creates the cognitive layer enabling autonomous defense systems to work together across different vendors and platforms. Builds novel algorithmic weapons and tactics orchestration for all-domain, cross-vendor systems serving Department of War and UK Ministry of Defense.
AI-native HR platform that combines senior HR executives and AI engineers to transform compensation management, recruiting, and performance review processes. Embeds 'forward-deployed' experts (former HR leaders from Nubank, XP, IBM) who work alongside AI engineers to design customized HR policies and bespoke software tools. Provides real-time compensation benchmarking data from over 1,000 companies. Serves 150+ Brazilian companies including Nubank, QuintoAndar, Creditas, and iFood.
Agentic AI decision intelligence platform built for retail. Unifies retailer strategy, internal data, and external competitive signals to deliver prioritized, explainable recommendations across pricing, promotions, inventory, marketing, and assortment. Serves retailers from $20M to $100B in revenue across three continents. Incubated within Landing AI (Andrew Ng).
AI-native intelligence platform helping businesses navigate and win government contracts. Makes public sector data accessible and actionable across 110,000+ agencies (cities, counties, state agencies, schools, special districts). Provides predictive intelligence on government purchasing decisions and automates public record requests at scale.
B2B cross-border payments infrastructure platform for Indian businesses. Provides API-driven infrastructure enabling SaaS companies, global capability centers, IT/ITeS exporters, and goods exporters to collect overseas payments, manage foreign exchange, and settle funds locally. Supports payments from 100+ countries across 25+ currencies, serving nearly 15,000 businesses with $1B in annualized cross-border payments.
AI platform that accelerates financial services decision-making using proprietary data. Connects structured and unstructured firm data across legacy systems (memos, models, accounting systems) and applies finance-specific intelligence to automate high-stakes decisions. Deploys directly into customer environments for data control. Institutions managing hundreds of billions in assets use it for portfolio monitoring, cross-cycle analysis, and credit optimization.
AI-native enterprise resilience platform that delivers verifiable, continuous data protection. Connects to all environments, security solutions, and backup tools to autonomously map infrastructure and backup data, uncovering gaps that break recovery plans. Turns data resilience from manual backup processes into automated, AI-powered capability for CISOs and IT leaders.
AI-native commercial insurance brokerage automating the insurance buying process for mid-sized businesses. The platform matches buyers to over 160 carriers across workers' compensation, general liability, professional liability, cyber, commercial auto, and bonds, using AI to route quotes, handle documents, and manage underwriter follow-ups. Serves 6,000+ customers across 35 states with a 98.78% retention rate.
AI training gym platform that provides infrastructure and environments for training, fine-tuning, and evaluating machine learning models. Offers standardized benchmarking and optimization tools for AI developers and researchers.
7Rivers is a technology services company and certified Snowflake Elite Partner that helps enterprises harness data and AI for real business value. Services span data migration, Data Vault 2.0 implementation, generative AI solutions, data science, and managed services across insurance, banking, software, manufacturing, and healthcare.
Coral Care is a pediatric therapy platform connecting families with licensed speech, occupational, and physical therapists who deliver insurance-covered services in the home. The platform supports clinicians in building flexible private practices through integrated infrastructure spanning credentialing, scheduling, documentation, and billing.
Builds an AI-powered platform for enterprise finance teams that automates the month-end close process. Uses agentic AI to handle reconciliations, journal entries, flux analysis, and variance reporting. Integrates with ERP systems like NetSuite and serves over 30 enterprise customers globally.
AI-native vulnerability management platform that deploys autonomous AI agents to investigate, prioritize, and remediate security vulnerabilities across the full lifecycle. Founded by ex-Abnormal Security and Coinbase engineers, Cogent works with dozens of Fortune 1000 companies and reports a 97% reduction in exposure windows for critical issues.
AI-native operating system for financial institutions, designed to systematize client data, onboarding, and servicing at scale. The platform unifies fragmented financial technology stacks into a single intelligent layer, integrating with CRMs, custodians, portfolio management tools, and underwriting systems.
ChipAgents (Alpha Design AI) is an agentic AI platform for semiconductor chip design and verification. The platform deploys coordinated AI agents that plan, reason, execute, and continuously improve across complex silicon programs, helping RTL design and verification engineers accelerate workflows by up to 10x. The company serves 80 leading semiconductor firms with multi-year licensing agreements.
Builds plug-and-play, system-level power management solutions for AI data centers and cloud infrastructure, designing configurable platform-based power architectures that span from grid to core.
Humanoid robotics company building the Apollo general-purpose robot for manufacturing, logistics, and retail. Spun out of the University of Texas Human Centered Robotics Lab in 2016.
Ricursive Intelligence is a frontier AI lab building AI systems to transform semiconductor design, founded by the co-creators of Google's AlphaChip.
This page tracks companies at the Series A stage (no Series B or later rounds on record). Companies are automatically removed once they raise beyond Series A. Data is compiled from verified sources including company announcements, press coverage, and regulatory filings.